Intacept injection 25 mg
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To check the solution whether it is clear or not The content of the prefilled syringe should be checked before administration, if the content is between the two purple fill level indicator lines, then the syringe should not used for administrationĭo not take out the needle cover hence permits the syringe to reach room temperature Intacept is a single-use prefilled syringe, before administration it should be allowed to kept in a room temperature Intacept is prefilled syringes, containing 25mg/0.5ml The recommended dosage is 0.4mg/kg up to 25mg per dose as given for twice-weekly maximum dose up to 0.8mg/kg in juvenile idiopathic arthritis Stop the therapy after 3 months, if no response occurs
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Patients with RA, AS & PsA: The recommended dosage of Intacept is 25mg as a two times a week at interval of 3 to 4 weeks RA: rheumatoid arthritis AS: Ankylosing spondylitis PsA: psoriasis arthritis The terminal half-life period of Intacept is 5 days with the clearance of 160 ± 80ml/min The peak plasma concentration reached only at 69 hours ± 34 hours after a single dose The Intacept is absorbed very slowly after administered subcutaneously The onset of action occurs within 1 to 2 weeks The bioavailability is occurred as 60% absolutely up to 76% Intacept exhibits its action by Etanercept is a dimeric dispersible form of p75 TNF receptor, can bind TNF fragment, thus results leads to prohibits merging of TNF-α & TNF-β to TNFRs cell surface and concludes as biologically passive These are present on a surface of the cells which is an insoluble form There are two specific receptors of TNF are In these conditions, TNF level are very high in range which is found in tissues and fluids of the infected patients Tumor necrosis factor is developing a natural cytokine which is involved in typical inflammatory and immune responses.Ĭytokine performed a vital role in inflammatory development in rheumatoid arthritis, polyarticular juvenile idiopathic arthritis, psoriasis arthritis, & Ankylosing spondylitis This condition is mostly occurs at the age of 2 years & older, Intacept is used alone to reduce the symptoms In this condition, Intacept injection is used to decrease the signs and symptoms of Ankylosing spondylitis
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In combination with methotrexate in patients who are not respond for methotrexate alone Intacept is used alone or combined with methotrexate which is involved in suppression of damage of arthritis. In rheumatoid arthritis, Intacept injection is combined with methotrexate or used alone to reduce the progression Intacept is ideally used in the conditions like Route of administration: Subcutaneous, single useĬategory: Disease-modifying Anti-rheumatoid arthritis, TNF prohibition, immunosuppressant Package: prefilled syringe containing 25mg of Etanercept for solution Intacept vial containing 25mg/0.5ml of Etanercept for a solution for subcutaneous injection. Intacept expels its action by inhibiting tumor necrosis factor which is produced by immune system Intacept is an injection available in a prefilled syringe. Intacept 25mg is an Intas pharmaceutical product, containing an active component called Etanercept. It should be used alone or in combination with other medicines which involved in the treatment of rheumatoid It should be avoided by people who are allergic to latex, are pregnant or are planning to do so, have been in close proximity to a person with chicken pox.Intacept 25mg injection is used in rheumatoid arthritis condition. It can also weaken the heart and lead to heart problems. It can also lead to nervous system problems such as sclerosis and seizures. The drug is especially dangerous for people with chickenpox. Patents with serious infections are advised to use it with caution and doctor's prescription. Some cases of cancers have also been reported in children. It can also aggravate or lead to serious conditions like fungal infections, sepsis, or tuberculosis. Some common side effects include pain, headache, itching, bruising, sore throat, redness, swelling and dizziness. Intacept 25Mg Injection is US FDA approved, but has some side effects as well.
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It is usually injected in the body and shows results in 2-10 weeks. Intacept 25Mg Injection blocks the TNF (tumor necrosis factor alpha) that causes inflammation. Intacept 25Mg Injection is a biological medicine which is used for treating inflammatory conditions such as rheumatoid arthritis, plaque psoriasis, ankylosing spondylitis, psoriatic arthritis, polyarticular juvenile idiopathic arthritis.